副肝左动脉对腹腔镜辅助胃癌根治术患者近期疗效的影响-肿瘤学专业论文.docxVIP

PAGE PAGE 2 Short-term Clinical Implications of the Accessory Left Hepatic Artery in Patients Undergoing Laparoscopy-assisted Radical Gastrectomy for Gastric Cancer Abstract Objective To evaluate the prevalence of the accessory left hepatic artery (ALHA) and its short-term clinical implications in patients undergoing laparoscopy-assisted radical gastrectomy for gastric cancer. Methods Clinical data of 1173 patients with gastric cancer who underwent laparoscopy-assisted radical gastrectomy between May 2007 and February 2012 were retrospectively analyzed. Groups of patients with and without ALHA were compared to identify differences in intraoperative and postoperative variables and changes in liver function. Results The ALHA defined as a vessel arising from the left gastric artery, which, together with a typical left hepatic artery, supplies blood to the left lobe of the liver. Of the 1173 patients, 135(11.5%) had an ALHA and 1038 (88.5%) did not. There were no significant between-group differences in clinicopathological and intraoperative characteristics, postoperative recovery, and morbidity and mortality rates (P0.05 each). None of the patients had postoperative symptoms associated with impaired liver function. Glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) and total bilirubin (TBIL) concentrations were similar preoperatively. TBIL concentrations on postoperative days 1, 3, and 7 were similar (P0.05), while GOT and GPT activities were higher in the ALHA than in the non-ALHA group on days 1 and 7 (P0.05), with all three markers similar in the two groups on day 14. In patients without chronic liver disease (CLD), GOT, GPT and TBIL concentrations were similar in patients with and without ALHA; whereas, in patients with CLD, GOT and GPT concentrations on days 1 and 3 and GOT on day 7 were higher in patients with than without ALHA. Conclusion ALHA is a common anomaly that was found in 11.5% of patients. It can be safely severed during ra