胺碘酮联合酒石酸美托洛尔治疗室性心律失常疗效评价.docVIP

胺碘酮联合酒石酸美托洛尔治疗室性心律失常疗效评价 　　【摘要】 目的：观察胺碘酮联合酒石酸美托洛尔治疗心律失常的疗效。方法：选择本院2010年3月-2013年3月收治的84例室性心律失常患者作为研究对象，随机均分为试验组和对照组，对照组在常规治疗的基础上单用酒石酸美托洛尔，试验组在常规治疗的基础上给予胺碘酮联合酒石酸美托洛尔治疗，比较两组患者的治疗效果。结果：试验组患者治疗总有效率显著高于对照组，差异具有统计学意义（P0.05）。结论：胺碘酮联合酒石酸美托洛尔治疗室性心律失常疗效显著优于单用酒石酸美托洛尔，无严重不良反应，安全有效。 　　【关键词】 胺碘酮； 酒石酸美托洛尔； 室性心律失常； 疗效 　　Curative Effects Evaluation of Amiodarone Combined with Metoprolol in Treatment of Ventricular Arrhythmias/AI Qing-ya.//Medical Innovation of China，2013，10（35）：037-038 　　【Abstract】 Objective： To observe the curative effects of Adodarone combined with Metoprolol in treatment of ventricular arrhythmias.Method： 84 cases of ventricular arrhythmias in our hospital from March 2010 to March 2013 were selected as the study objects and randomly divided into the experimental group and control group.The control group were added Metoprolol only on the basis of conventional treatment，and the experimental group were added Amiodarone combined with Metoprolol on the basis of conventional treatment.The course was 6 months.The curative effects of these two groups were compared.Result：The total effective rate of experimental group after the treatment was higher than that of the control group， the difference had statistical significance（P0.05）. Conclusion： The curative effect of Adodarone combined with Metoprolol in treatment of ventricular arrhythmias was significantly better than that of Metoprolol only， and there were no severe adverse reactions， which was safety and effective. 　　【Key words】 Amiodarone； Metoprolol； Ventricular arrhythmias； Curative effects 　　First-author’s address：Xinyu People’s Hospital， Xinyu 338000，China 　　doi：10.3969/j.issn.1674-4985.2013.35.018 　　室性心律失常是心血管内科的常见病症，是指源于心室的心律紊乱，主要包括室性心律失常、室性早搏、心室颤动等[1-2]，不仅是造成器质性心脏病患者发病和死亡的主要原因，还是导致非心脏病患者猝死的主要原因之一。由于体内心室是心脏泵血供应的承担者，心律失常会导致患者血流动力不稳定，使心脏供应功能恶化，出现心力衰竭、低血压等现象，从而加重心脏的负担，有可能会引发猝死[3]。经过相关研究，在系列的治疗方案当中，药物治疗是目前最常用的治疗方法、方式[4-6]。胺碘酮是一种安全的抗心律失常药物，其疗效确切，直接延长动作电位时程、复极时间和不应期，特别是对室性心律失常的疗效非常显著。β受体阻滞剂可以减少室性心律失常发生，对于室颤、降低心