微生物组分析技术的发展趋势：从单细胞功能成像到菌群大数据精选.pdfVIP

Engineering 3 (2017) 66–70 Contents lists available at ScienceDirect Engineering journal homepage: /locate/eng Research Microecology—Perspective Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data a,e, a,e a,e a,e d d c b, Jian Xu *, Bo Ma , Xiaoquan Su , Shi Huang , Xin Xu , Xuedong Zhou , Wei E. Huang , Rob Knight * a Single-Cell Center, CAS Key Laboratory of Biofuels, Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China b Center for Microbiome Innovation, Department of Pediatrics, Department of Computer Science and Engineering, University of California, San Diego, CA 92093, USA c Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK d State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China e University of Chinese Academy of Sciences, Beijing 100049, China a r t i c l e i n f o a b s t r a c t Article history: Method development has always been and will continue to be a core driving force of microbiome science. Received 14 January 2016 In this perspective, we argue that in the next decade, method development in microbiome analysis will be Revised 25 January 2017 driven by three key changes in both ways of thinking and technological platforms: ① a shift from dissect- Accepted 17 Februar