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cochrane评分表
Risk of bias Item Authors judgement Description Adequate sequence generation? Yes Prinicipal author stated that computer generated allocation was used Allocation concealment? Yes Prinicipal author stated that allocation was concealed Blinding? Unclear No mention of study personnel or participants being blind to treatment group Incomplete outcome data addressed? Yes All participants accounted for, one drop out recorded but included by us in analysis Free of other bias? Unclear Possible uneven distribution of complete and incomplete paralysis at start of study between the two treatment groups Cochrane RCT质量评价标准:随机方法是否正确。是否隐蔽分组。盲法的使用情况。失访或退出描述情况,有无采用意向性(ITT)分析。以上质量标准中,如所有标准均为“充分”,则发生各种偏倚的可能性很小;如其中一条为不清楚,则有发生相应偏倚的中等度可能性;如其中一条为“不充分”或“未采用”,则有发生相应偏倚的高度可能性。可参见:RCT的质量评价标准选择总结 /bbs/topictpg=1age=-1 Quality assessmentThe quality of the trials was assessed and graded independently by two authors according to the criteria described in The Cochrane Handbook 4.2.6 (Higgins 2006). Gradings were compared and any inconsistencies between the authors in the interpretation of inclusion criteria and their significance to the selected study were discussed and resolved.The selected study was assessed for the following characteristics:1. The adequacy of the randomisation process (possible selection bias). Adequate randomisation includes any one of the following methods: computer generated or table of random numbers, drawing of lots, coin-toss, shuffling cards or throw of a dice. Inadequate methods of randomisation include the following: case record number, date of birth or alternate numbers.2. The adequacy of the allocation concealment (possible selection bias). Adequate methods of allocation concealment include either central randomisation (i.e. separate to other aspects of trial administration) or sequentially numbered sealed opaque envelopes. Inadequate concealment means an open allocation sequence in which either participants or trialists were able to fore
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