大剂量阿司匹林改善急性脑梗死患者神经功能缺损效果观察.docVIP

精品论文 参考文献 大剂量阿司匹林改善急性脑梗死患者神经功能缺损效果观察 刘春侠 　　（夏邑县第二人民医院西药房 河南夏邑 476400） 　　【摘要】目的:探究大剂量阿司匹林治疗急性脑梗死患者的临床疗效。方法：选取2014年3月到2015年1月期间我院诊确诊为急性脑梗死的60例患者作为研究对象，对照组给予小剂量阿司匹林（100mg/d）口服治疗，实验组给予大剂量阿司匹林（300mg/d）进行治疗，对比两组治疗效果。结果：实验组神经功能缺损评分降低程度明显高于对照组，两组对比差异显著（P＜0.05）；实验组治疗有效率为93.3%，高于对照组的73.3%，两组对比差异显著（P＜0.05）；实验组不良反应发生率为10.0%，与对照组的6.7%相比较，无明显差异（P＞0.05）。结论：大剂量阿司匹林治疗急性脑梗死疗效显著，更有利于患者临床症状的改善，且不良反应无明显增加，值得推广应用。 　　【关键词】阿司匹林；急性脑梗死；神经功能缺损 　　【中图分类号】R742 【文献标识码】A 【文章编号】1007-8231（2015）23-0029-02 　　Large doses of aspirin improve nerve function defect effect observed in patients with acute cerebral infarction Liu Chunxia. 　　The Second Peoples Hospital Pharmacy Xiayi county, Henan Xia Yi 476400,China 　　【Abstract】Objective To explore the large dose of aspirin treatment in patients with acute cerebral infarction clinical curative effect. Methods Selecting during March 2014 to January 2015 in our clinical diagnosis of acute cerebral infarction, 60 cases of patients as the research object, the control group given low-dose aspirin (100 mg/d) oral treatment, the experimental group given large doses of aspirin (300 mg/d) treatment, compared two groups of therapeutic effect. Results The neural function defect scale reduced significantly higher than that of control group, two groups compared significant difference (P lt; 0.05); The experimental treatment effective rate was 93.3%, 93.3% higher than that of control group, two groups compared to significant difference (P lt; 0.05); Experimental group the incidence of adverse reactions was 10.0%, compared with 6.7% in the control group, no significant difference (P gt; 0.05). Conclusion High-dose aspirin treatment of acute cerebral infarction curative effect is distinct, more conducive to the improvement of clinical symptoms, and no obvious increase adverse reactions, is worthy of popularization and application. 　　【Key words】Aspirin; Acute cerebral infarction; Neurologic deficits 　　急性脑梗死是一种较为常见的心脑血管疾病，是由多种因素引起