VEGF-C及VEGFR-3在食管鳞癌组织中的表达及与淋巴结转移的关系.pdfVIP

现代肿瘤医学 2013年 10月 第21卷第 l0期 MODERNONCOLOGY，Oct．2013，VOL．21，NO．10 ．2233． [8] NakamuraH，TaniguchiY，MiwaK，eta1．Comparisonofthesurgi— SUS$omcotomfornon—small—celllungcancer[J]．AsianPacJ caloutcomesofthoracoscopiclobectomy，segmenteetomy，andwedge CnacerPrev，2012，13(2)：44—5O． resectionforclinicalstageInon—smallcelllungcancer[J]．The— [1O] 杨磊，张锦林，谭清和，等．中晚期肺癌患者生存质量的研究进 racCardiovascSurg，2011，59(3)：137—141． 展[J]．现代肿瘤医学，2011，19(9)：1869—1871． [9] PanTW ，WuB，XuZF，eta1．Video—assistedthoracicsurgeryver- (编校：谈静) VEGF—CJ~VEGFR一3在食管鳞癌组织中的表达及与淋巴结转移的关系 廖和和 ，李建军 ，吴树强 ，李寒春 ，金 磊 ExpressionofVEGF——CandVEGFR——3inesophagealsquamouscellcarcinomatissues andtherelationshipwithlymphnodemetastasis LiaoHehe，LiJianjun，WuShuqiang，LiHanchun ，JinLei DepartmentofThoracicandOntologySurgery，FirstAffiliatedHospital，XianMedicalCollege，ShaanxiXian710077，Chi- na；DepartmentofSurgery，HospitalofChineseMedicineofLintongDistrict，ShaanxiXi~an710600，China． A【bstract】 0bjective：ToinvestigatetheexpressionofVEGF—CandVEGFR一3inesophagealcarcinomatissues andtherelationshipwithlymphnodemetastasis，analyzethefunctionofVEGF—C andVEGFR 一3infacilitatinge- sophageal carcinomametastasis．Methods：Tosummarizetheclinicaldataof48cases，theexpressionofVEGF—C andVEGFR一3in4of48casesweredetectedbyWestern blot，theresuhswereevaluatedwithclinical factorstogeth— er．therelationbetweenVEGF—C andVEGFR 一3 andesophagealcarcinomametastasiswasanalyzed．Results：The expressionofVEGF—C inesophagealcarcinomatissueswashigherthanprecanceroustissuesnadnormal esophageal tissues，whereas，theexpressionofVEGFR一3inesophageal carcinomatissuesshowednodifferencewithprecancer- OUStissuesandnormal esophageal tissues．In specimensofpatientswithlymphnodemetastasis，theexpressionsof VEGF—CandVEGFR一3inesophagealcarcinomatissueswerebothhigherthanspecimensofpatientswihtoutlymph