膜增殖性肾小球肾炎与c3肾小球肾病排解疑惑-nature.pdfVIP

SK Olsen and RS Brown Jr: Hepatitis B treatment full translations © 2012 International Society of Nephrology 膜增殖性肾小球肾炎与C3肾小球肾病：排解疑惑 Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion 1 2,3,4 2,3,4 Sanjeev Sethi , Carla M. Nester and Richard J.H. Smith 1 2 Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, Iowa City, Iowa, USA; 3Division of Nephrology, Department of Internal Medicine, Carver College of Medicine, University of lowa, Iowa City, Iowa, USA and 4Division of Nephrology, Department of Pediatrics, Carver College of Medicine, University of lowa, Iowa City, Iowa, USA Correspondence: Richard J.H. Smith, Division of Nephrology, Department of Internal Medicine, University of Iowa, 21151 PFP, 200 Hawkins Drive, Iowa City, Iowa 52242, USA or Division of Nephrology, Department of Otolaryngology, University of Iowa, 21151 PFP, 200 Hawkins Drive, Iowa City, Iowa 52242, USA. E-mail: richard-smith@ 在线发表于 年 月 日 Kidney International (2012) 81, 434–441; doi:10.1038/ki.2011.399; 2011 12 7 摘要：膜增殖性肾小球肾炎（MPGN）是肾小球损伤的 对于MPGN ，采用电镜可以确定电子致密沉积物与肾小球基底 一种普通模式，在光镜下很容易识别。采用进一步的检查，可 膜的相对关系，例如，电子致密物沉积于内皮下、膜内 （致密层） 或内皮下及上皮下。根据这些差异， 通常可分为 型 以区分MPGN的亚型。例如，电镜可发现电子致密物沉积的差 MPGN MPGN I 1-4 （ ）、