九里香化学成分和药理作用的研究进展.pdfVIP

·1172 · 现代药物与临床 Drugs Clinic 第 30 卷 第 9 期 2015 年 9 月 九里香化学成分和药理作用的研究进展 1 2 2 2* 郭 培 ，柳 航 ，朱怀军 ，葛卫红 1. 南京中医药大学中西医结合鼓楼临床医学院，江苏 南京 210029 2. 南京大学医学院附属鼓楼医院 药学部，江苏 南京 210008 摘 要：九里香为芸香科九里香属植物，广泛分布于我国的南部以及亚洲一些热带和亚热带地区。目前，从中分离得到的化 学成分主要有香豆素类、黄酮类、生物碱类以及挥发油等。现代药理研究表明，九里香具有杀虫、消炎镇痛、抗菌及抗氧化 等作用。综述了九里香化学成分和药理作用的研究进展，为其药效物质基础、作用机制研究及开发利用提供理论依据。 关键词：九里香；化学成分；药理作用 中图分类号：R284 ；R285 文献标志码：A 文章编号：1674 - 5515(2015)09 - 1172 - 07 DOI: 10.7501/j.issn.1674-5515.2015.09.029 Research progress on chemical constituents and biological activities of Murraya exotica 1 2 2 2 GUO Pei , LIU Hang , ZHU Huai-jun , GE Wei-hong 1. Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210029, China 2. Department of Pharmacy, Affliated Drum Tower Hospital of Nanjing University, Nanjing 210008, China Abstract: Murraya exotica , a kind of plant in genus Murraya Koenig ex L. of Rutaceae family, is widely distributed in southern China and some tropical and subtropical regions of Asia. At present, the bioactive chemical constituents from this plant are mainly composed of coumarins, flavonoids, alkaloids, volatile oil, etc. Modern pharmacological researches show that M. exotica has insecticidal, anti-inflammatory analgesic, antibacterial, antioxidant effects, etc. The research progress on chemical constituents of M. exotica and their pharmacological activities are reviewed in this paper, which could provide a theoretical basis for the material basis of efficacy, mechanism of action and exploitation. Key words: Murraya exotica L.; chemical constituents; pharmacological activities 九里香Murraya exotica L.为芸香科九里香属植 展，为其药效物质基础、作用机制研究及开发利用 物，主要分布在我国云南、贵州、湖南、广东、广 提供了理论依据。 西、福建、海南