斯蒂文斯-约翰综合症（Stevens John syndrome）.docVIP

斯蒂文斯-约翰综合症（Stevens John syndrome） Stevens-Johnson syndrome Help edit an encyclopedia In 1922, the Stevens-Johnson syndrome was first described in detail by Stevens and Johnson. The syndrome is a kind of acute Stevens-Johnson blister lesions involving skin and mucous membrane syndrome can occur in certain infections or some oral medicines after erythema multiforme is mild skin bullous erythema multiforme lesions, further development of the formation of toxic epidermal necrolysis, this is an acute fatal disease. The ocular manifestations of the disease are serious. The lesions can involve the cornea, conjunctiva, bulbar conjunctiva and eyelid. Catalog epidemiology Pathogeny Pathogenesis Clinical manifestation Diagnosis therapeutic diagnosis inspect Treatment Prognostic epidemiology Pathogeny Pathogenesis Clinical manifestation Diagnosis therapeutic diagnosis inspect Treatment prognosis Expand the epidemiology of this section 1., the incidence of Stevens-Johnson syndrome is low. Char et al reported only 4.2 of every 1 million people had Stevens-Johnson syndrome each year. Schoph et al reported that the annual incidence of Stevens-Johnson syndrome in Germany was 1.1/100 million. France reported the incidence of 1.2/100 million to 1.3/100 million per year, while the incidence of Italy was 0.6/100 million. At present, there is no report of Stevens-Johnson syndrome incidence in china. 2. the incidence of ocular complications. 80% of patients with Stevens-Johnson syndrome present eye complications. In some severe cases, acute complications include keratitis, corneal perforation, and severe endophthalmitis. Chronic complications include conjunctival scarring, entropion, dry eye and eyelid adhesion. These complications can lead to secondary corneal damage, which can lead to long-term complications, which can cause significant visual changes in patients with 1/3s Stevens-Johnson syndrome. The incidence of complications in AIDS patients is obviously higher because of the decr