中波紫外线照射治疗绝经后骨质疏松临床探究.docVIP

中波紫外线照射治疗绝经后骨质疏松临床探究 　 作者：武密山 赵素芝 武中建 张洁 【摘要】 目的 探讨中波紫外线照射仪对绝经后骨质疏松的治疗作用。方法 选择符合诊断标准的绝经后骨质疏松患者99例随机分为A、B、C三组,在A组35例肾阳虚型绝经后骨质疏松患者用中波紫外线照射治疗;B组34例肾阴虚型绝经后骨质疏松患者用中波紫外线照射治疗，两组均加服钙剂(2 g/ d)。对照组C组，30例绝经后骨质疏松患者肌注鲑鱼降钙素,同时加服钙剂 (2 g/ d)。观察治疗前后血清1,25(OH)2D3、Young Z、腰椎骨密度(BMD)的变化。结果 中波紫外线照射治疗肾阳虚组血清1,25(OH)2D3、Young Z、腰椎BMD在治疗前后差异均有显著性，与肾阴虚组比较有显著差异。C组各观察指标无明显变化。结论 中波紫外线照射对绝经后肾阳虚型骨质疏松有较好的疗效,可提高骨密度,改善骨代谢。 【关键词】 中波紫外线照射仪;肾阳虚;绝经后骨质疏松;骨密度;1,25(OH)2D3 　　【Abstract】 Objective To study the role of UVB irradiate instrument in the patients with postmenopausal osteoporosis. Methods 99 postmenopausal osteoporosis patients were randomly divided into A， B and C groups. In group A， 35 patients with deficiency of kidneyyang postmenopausal osteoporosis were given irradiation with UVB irradiate instrument. In group B， 34 patients with deficiency of kidneyyin postmenopausal osteoporosis were given irradiation with UVB irradiate instrument. And in the two groups， they were took elementary calcium (2 g/ d) . In the control group C， 30 patients with postmenopausal osteoporosis were injected salmon calcitonin (CT) and were took elementary calcium (2 g/ d).The serum 1,25(OH)2D3 and the Young Z and bone mineral density (BMD) change were detected before and after the treatment. Results The levels of serum 1,25(OH)2D3 and Young Z and BMD were significantly increased in the deficiency of kidneyyang group after UVB irradiate instrument and there was no change in group C. The effective rate was 90%, there was remarkably difference after treatment than before in the deficiency of kidneyyin group. Conclusions UVB irradiate instrument is an effective cure in the improvement of bone metabolism of osteoporosis. 　　【Key words】 UVB irradiate instrument ;Deficiency of kidneyyang;Postmenopausal osteoporosis;Bone mineral density (BMD);1,25(OH)2D3 　　研究表明，补肾阳中药可明显抑制骨吸收、促进骨形成、有效地防治骨质疏松〔1〕。近年来，国内学者相继研制出UVB灯，并进行了钙磷代谢〔2〕、辐射损伤〔3〕及抗骨质疏松的动物实验研究〔4〕。根据“天人相应”，肾阳来自太阳光照，本文以骨质疏松患者为研究对象，观察接受不同强度的太阳光照射对肾阳虚型及肾阴虚型骨质疏松患者1，25(OH