biocompatibility of collagen membranes assessed by culturing human j111 macrophage cells胶原蛋白膜的生物相容性评估人类j111巨噬细胞细胞培养.pdfVIP

Materials 2009, 2, 945-957; doi:10.3390/ma2030945 OPEN ACCESS materials ISSN 1996-1944 /journal/materials Article Biocompatibility of Collagen Membranes Assessed by Culturing Human J111 Macrophage Cells 1 2 2 2 Claudia Gaetana Aruta , Maria Antonietta Croce , Daniela Quaglino , Deanna Guerra and Roberta Tiozzo 2,* 1 Department of Biomedical Sciences, Section of Biochemistry, University of Modena and Reggio Emilia, Via G. Campi 287, 41100 Modena, Italy; E-Mail: claudiagaetana.aruta@unimore.it (C.G.A.) 2 Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia, Via G. Campi 287, 41100 Modena, Italy; E-Mails: mariaantonietta.croce@unimore.it (M.A.C.); daniela.quaglino@unimore.it (D.Q.); deanna.guerra@unimore.it (D.G) * Author to whom correspondence should be addressed; E-Mail: roberta.tiozzo@unimore.it; Tel. +39-059-205-5422; Fax: +39-059-205-5426 Received: 29 June 2009; in revised form: 4 August 2009 / Accepted: 14 August 2009 / Published: 18 August 2009 Abstract: We have carried out an in vitro study on the interactions of human macrophages (J111 cell line) with different scaffolds made of type I and II collagen, isolated from horse tendon and from horse articular and trachea cartilage, in order to assess growth properties and biocompatibility of these membranes. We have therefore evaluated cell adhesion and proliferation as well as cytokine production consi