冠通方对老年冠心病患者超敏C反应蛋白影响.docVIP

冠通方对老年冠心病患者超敏C反应蛋白影响 　【关键词】 冠状动脉疾病;C反应蛋白质;冠通方 　　Effect of Guantongfang on highsensitivity Creactive protein in elder patients with coronary artery disease 　　WANG Qiang, YI ZiGang, HE JinSong, SU YiQiang, MO YunQiu, ZHANG ShuangQi, YANG LiQiang, ZHANG YiKun, PANG LunXiang, GU GuoLong, GAO Peng 　　Department of Cardiology, Ruikang Hospital, Guangxi College of Traditional Chinese Medicine, Guangxi 530011, China, Guangxi College of Traditional Chinese Medicine, Guangxi 530001, China 　　【Abstract】 AIM: To observe the effect of Guantongfang (GTF, mainly composed of radix notoginseng, salvia miltiorrhiza, lumbricus, snakegourd fruit, dry radix ginseng, gold theragran, dried tangerine peel and ophiopogonis tuber) on the content of the highsensitivity Creactive protein (hsCRP) in the elder patients of coronary artery disease. METHODS: Sixty elder patients of coronary artery disease were randomly allocated to groups A and B and treated respectively with GTF together with routine western medicine(n=30) and mere routine western medicine(n=30), all with a course of 4 weeks. RESULTS: After treatment, the concentration of the hsCRP in the 2 groups differed obviously（Plt;0.01）; in relieving symptoms and in improving electrocardiogram(ECG) group A was better than group B（Plt;0.05 or Plt;0.01）.CONCLUSION: The treatment effect of GTF together with routine western medicine is superior to that of the simple routine western medicine. 　　【Keywords】 Guantongfang; Coronary disease; CReactive protein 　　【摘要】目的： 探讨冠通方对冠心病超敏C反应蛋白浓度的影响. 方法： 将60例冠心病老年患者,随机分成冠通方（由田七、丹参、地龙、瓜蒌、生晒 参、绞股蓝、陈皮、麦冬组成）加西药治疗组（治疗组A组）30例;西药治疗组（对照组B组）30例. 4 wk为1疗程. 结果： 经治疗后两组冠心病超敏C反应蛋白的浓度有显著性差异（Plt;0.01），治疗组的症状疗效、心电图疗效均优于对照组（Plt;0.05或Plt;0.01）. 结论： 冠通方组降低超敏C反应蛋白浓度优于单纯对照组. 　　【关键词】　冠状动脉疾病;C反应蛋白质;冠通方 　　0引言 　　 　　炎症因子在冠状动脉粥样硬化性心脏病(Coronary Artery Disease，简称冠心病，CAD)的发病中起着重要作用，反映急性炎症反应的血清超敏C反应蛋白(highsensitivity Creactive protein, HsCRP)是冠心病的独立危险因子之一［1］，为探讨具有益气养阴，清热解毒化痰，行气活血化瘀通络作用的冠通方治疗冠心病对HsCRP浓度的影响，我们对200506/200606住院的60例冠心病的老年患者进行了HsCRP