毛冬青中环烯醚萜苷类化合物的分离及鉴定_杨鑫.pdfVIP

17 3 Vol117 No13 p. 173 2007 6 77 Chinese Journal of Medi inal Chemistry Jun12007 Sum 77 : 1005- 0108( 2007) 03- 0173- 05 1 2 2 杨 鑫 , 丁怡, 张东明 ( 11 , 150090; 21 , 100050) : , IRNMRMS 7 , oleoa teoside( 1) - 11- ( 2) ( 3) ( R )-B- ( 4) ( 8Z )-ligstroside( 5) ( 8E )- ( 6) 2c-( 3c, 4c- ) -( 6d- O- - 11- )-B-D- ( 7) 7 : ; ; ; : R284 : A Isolation and identification of iridoid glycosides from I lex p ubescens 1 2 2 YANG Xin , DING Yi , ZHANG Dong-ming ( 1. School of Food Science and Engineering,Harbin Institute of Technolog , Harbin 150090, China; 2. Institute of Materia Medica, ChineseA cadem of Medical Science and Peking Union Medical College, Beij ing 100050, China) Abstract:AimTo study hemi al onstituents from Ilex p ubescens. Methods The onstituents w ere isolated by hromatographi method and the stru tures w ere identified on the basis of spe tral analysis in luding IR, NM R, and MS te hniques. Results and conclusion Seven iridoid gly osides w ere identified as oleoa teoside ( 1) , oleoside 11-methyl ester( 2) , oleuropein( 3) , ( R)-B-hydroxyoleuropein( 4) , ( 8Z)-ligstroside( 5) , ( 8E )- nuezhenide( 6) , 2c-( 3c, 4c-dihydroxyphenyl) ethy-l ( 6d- O-oleoside- 11-methyl ester)- B-D-glu opyranoside ( 7) . All of them w ere isolated from Ilex p ubescens for the first time. Key ords:stru tural identifi ation; olumn hromatography; Ilex p ubescens Hook. et Arn. ; iridoid gly osides ( I lex 7 , p ubescens Hook. et Arn. ) , oleoa teoside( 1) ,