analysis of normal-tumour tissue interaction in tumours prediction of prostate cancer features from the molecular profile of adjacent normal cellsnormal-tumour组织互动的分析预测前列腺癌的肿瘤分子相邻的正常细胞的功能.pdfVIP
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analysis of normal-tumour tissue interaction in tumours prediction of prostate cancer features from the molecular profile of adjacent normal cellsnormal-tumour组织互动的分析预测前列腺癌的肿瘤分子相邻的正常细胞的功能
Analysis of Normal-Tumour Tissue Interaction in
Tumours: Prediction of Prostate Cancer Features from
the Molecular Profile of Adjacent Normal Cells
1,6 2 3 4 1
Victor Trevino , Mahlet G. Tadesse , Marina Vannucci , Fatima Al-Shahrour , Philipp Antczak , Sarah
1 8,9 4 5,7 1
Durant , Andreas Bikfalvi , Joaquin Dopazo , Moray J. Campbell , Francesco Falciani *
1 School of Biosciences and IBR, University of Birmingham, Edgbaston, United Kingdom, 2 Department of Epidemiology Biostatistics, University of Pennsylvania School
of Medicine, Philadelphia, Pennsylvania, United States of America, 3 Rice University, Houston, Texas, United States of America, 4 Bioinformatics Department, Centro de
´ ´
Investigacion Prıncipe Felipe, Valencia, Spain, 5 Institute of Biomedical Research, School of Medicine, The Birmingham University, Birmingham, United Kingdom,
´
6 Computer Science Department Biomedical Engineering Program, Instituto Tecnologico y de Estudios Superiores de Monterrey, Nuevo Leon, Mexico, 7 Department of
Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, United States of America, 8 INSERM U920, Talence, France, 9 University Bordeaux I,
Talence, France
Abstract
Statistical modelling, in combination with genome-wide expression profiling techniques, has demonstrated that the
molecular state of the tumour is sufficient to infer its pathological state. Thes
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