a public htlv-1 molecular epidemiology database for sequence management and data mining一个公共htlv 1分子流行病学数据库序列管理和数据挖掘.pdfVIP
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a public htlv-1 molecular epidemiology database for sequence management and data mining一个公共htlv 1分子流行病学数据库序列管理和数据挖掘
A Public HTLV-1 Molecular Epidemiology Database for
Sequence Management and Data Mining
1. 2. 3,5 5
Thessika Hialla Almeida Araujo , Leandro Inacio Souza-Brito , Pieter Libin , Koen Deforche ,
4 1 3,6
Dustin Edwards , Antonio Eduardo de Albuquerque-Junior , Anne-Mieke Vandamme ,
Bernardo Galvao-Castro1,2, Luiz Carlos Junior Alcantara1,2*
1 Gonc¸alo Moniz Research Center/Oswaldo Cruz Foundation, Salvador, Bahia, Brazil, 2 Bahia School of Medicine and Public Health/Bahia Foundation for Science
Development, Salvador, Bahia, Brazil, 3 Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium, 4 Animal Models and Retroviral Vaccines
Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, 5 MyBioData, Rotselaar,
´
Belgium, 6 Centro de Malaria e outras Doenc¸as Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
Abstract
Background: It is estimated that 15 to 20 million people are infected with the human T-cell lymphotropic virus type 1
(HTLV-1). At present, there are more than 2,000 unique HTLV-1 isolate sequences published. A central database to
aggregate sequence information from a range of epidemiological aspects including HTLV-1 infections, pathogenesis,
origins, and evolutionary dynamics would be useful to scientists and physi
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