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a new antigen retrieval technique for human brain tissue一个新的抗原检索技术对人类大脑组织
A New Antigen Retrieval Technique for Human Brain
Tissue
´ ´ 1. 1,2. 3,4 3,4 ´
Raul Alelu-Paz , Ignacio Iturrieta-Zuazo , William Byne , Vahram Haroutunian , Mercedes Garcıa-
5 ´ 6 ´ ´ 1,2 ´ 1 ´ ´ 1
Villanueva , Alberto Rabano , Marıa Garcıa-Amado , Lucıa Prensa , Jose Manuel Gimenez-Amaya *
´ ´ ´ ´
1 Departamento de Anatomıa, Histologıa y Neurociencia, Facultad de Medicina, Universidad Autonoma de Madrid, Madrid, Spain, 2 Laboratorio de Neuromorfologıa
´
Funcional, Clınica Universitaria, Universidad de Navarra, Pamplona, Spain, 3 Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States
´ ´ ´
of America, 4 Bronx Veterans Affairs Medical Center, Bronx, New York, United States of America, 5 Departamento de Anatomıa Patologica, Hospital Ramon y Cajal, Madrid,
´ ´
Spain, 6 Laboratorio de Neuropatologıa, Hospital de Alcorcon, Madrid, Spain
Abstract
Immunohistochemical staining of tissues is a powerful tool used to delineate the presence or absence of an antigen. During
the last 30 years, antigen visualization in human brain tissue has been significantly limited by the
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