Clinical practice to identify acute and chronic renal injury determination nail creatinine content（临床实践确定急性和慢性肾损伤指甲肌酐测定内容）.doc

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2017-09-05 发布于浙江
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Clinical practice to identify acute and chronic renal injury determination nail creatinine content（临床实践确定急性和慢性肾损伤指甲肌酐测定内容）.doc

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Clinical practice to identify acute and chronic renal injury determination nail creatinine content（临床实践确定急性和慢性肾损伤指甲肌酐测定内容）

Clinical practice to identify acute and chronic renal injury determination nail creatinine content In clinical work, we often encounter kidney injury in the performance of previous patients with renal status is unclear, especially the history is unclear ultrasound kidney size without significant change in the identification of acute renal injury, chronic renal injury often difficulties. the conventional serum creatinine determination can only reflect the level of renal blood, nails in creatinine content nail in the formation of a root serum creatinine level reflects three months ago, and a positive linear related to [1], and has nothing to do with the nails done when the serum creatinine level of clinical work, which collect the cases, data correlation detection, and organize data as follows: 1 objects and methods 1.1 Objects 1.1.1 healthy people group of 25 patients: 13 males and 12 females, aged 16-54, average 32 years old. 1.1.2 acute renal injury group, 20 cases: 12 males and 8 females, age 15-46 years, mean 34 years, in all cases meet the acute renal injury diagnostic criteria [2]. 1.1.3 chronic renal injury group of 30 patients: 18 males and 12 females, aged 20-65 years old, with an average 46-year-old, in all cases in line with chronic renal injury diagnostic criteria [3]. 1.2 Methods 1.2.1 three groups of patients underwent treatment the day cubital vein mining non anticoagulant 3ml, 4000rpm ?5min, the supernatant was measured in serum creatinine (Scr), .3 months of follow-up, the three groups of patients were measured in nail creatinine (Ncr) and serum creatinine (Scr). 1.2.2 nails creatinine leaching solution preparation: All cases were cut hands 10 fingers nail free end of the 1-2mm nails, nail clippings after sandpaper polished, washed, dried, crushed and sieved (40 mesh), weighed 30mg nail powder, distilled water was added 5ml, the thermostat (45 ℃) water bath oscillator sustained oscillation 6h, and then thermostat