Childrens immune thrombocytopenia megakaryocyte cell number and prognosis observed（儿童免疫血小板减少巨核细胞细胞数量和预后观察）.doc

Children’s immune thrombocytopenia megakaryocyte cell number and prognosis observed [Abstract] Objective To observe the immune thrombocytopenia (ITP) in children with bone marrow megakaryocytes and prognosis of the relationship between methods of statistical analysis of clinical data of our hospital for the past five years, 89 cases of newly diagnosed children with ITP and bone marrow cytology data, explore bone marrow megakaryocyte number and prognosis in children with ITP. results, the more the number of newly diagnosed children with ITP megakaryocytes, treatment, and the better the prognosis. Conclusion children with ITP bone marrow megakaryocytes and their efficacy and prognosis are closely related, and thus available megakaryocyte number of early prediction of the efficacy and prognosis of children with ITP. [Keywords:] the number of bone marrow megakaryocytes immune thrombocytopenia prognosis Immune thrombocytopenia (immune thrombocytopenia with ITP children the most common bleeding disorder, also known as idiopathic thrombocytopenic purpura (idiopathicthrombocytopenicpurpura ITP), a cellular and humoral immune to participate in the autoimmune diseases. sheets nuclear platelet - a large number of macrophage phagocytosis plexus caused by reduced peripheral blood platelet count. typical ITP patients bone marrow megakaryocytes is generally increasing, this increase is considered to be thrombocytopenia stimulate megakaryocyte precursor cells compensatory hyperplasia, clinical observation, part of ITP patients megakaryocytes is not increased, the proliferation of megakaryocytes is not obvious or reduce the patients may exist barriers to bone marrow megakaryocytes generated [1] and bone marrow stem cells or megakaryocytes intrinsic defects [2]. I also found in the clinical work, some of efficacy and a better prognosis in children often pre-treatment examination of bone marrow megakaryocytes, and less efficacy and poor prognosis in children with pre-treatme