Chickenpox one cases of acute lymphoblastic leukemia merger（水痘一个例急性淋巴细胞白血病合并）.doc

Chickenpox one cases of acute lymphoblastic leukemia merger : Geyan Li Dai Yongli Wang Junxia [Keywords:] acute lymphoblastic leukemia, varicella, herpes zoster Clinical data of 12 treated children with acute lymphoblastic leukemia with varicella zoster infection in 1 case, female, 4.5 years the children have entered the maintenance phase at the end of a admission to adopt VDLP (vincristine, the soft red adriamycin, asparaginase, prednisone programs appear weak, intermittent abdominal discomfort, body temperature 36.5 ℃ ~ 37.2 ℃, and the next day had scattered the typical rash appears in a blister-like rash, 24 h, mainly in the course of the first on the 20th in the head, neck, face, torso, limbs scattered distribution of the check: WBC 2.2 × 109 / L, platelets 32 ?109 / L, hemoglobin 113 g / L, and the diagnosis of acute lymphoblastic leukemia complicated chickenpox. intravenous high dose gamma globulin, SHL, acyclovir drug for treatment on the 3rd of severe nausea, vomiting, water and electrolyte disorders, coagulation abnormalities, such as performance, consider adrenal crisis. disable oral prednisone, intravenous application of hydrocortisone, to correct dehydration and electrolyte imbalance, but the patients condition deteriorated sharply, appear pale gray, fine clock speed, lower blood pressure, cold distal extremities, skin blur, dark urine, yellow and less vomit brown, skin petechia, ecchymosis, and eventually children died due to critical condition, treatment. Discuss acute lymphoblastic leukemia in children during one of the most common malignancy, with the improvement of chemotherapy and standard treatment, 5 a disease-free survival has been significantly improved [1]. Leukemia chemotherapy cycle, easily repeated and concurrent serious infection [2] In addition to common bacterial, fungal infection, the virus, in particular, is a highly contagious viral infection can not be ignored. Therefore, in addition to small strengthen strengthened,