肾病综合征的六大并发症详解（Detailed explanation of six major complications of nephrotic syndrome）.docVIP

肾病综合征的六大并发症详解（Detailed explanation of six major complications of nephrotic syndrome） Detailed explanation of six major complications of nephrotic syndrome Nephrotic syndrome can cause a variety of complications, Shijiazhuang nephrology hospital nephrology experts here to explain in detail the six major complications of nephrotic syndrome problems. The main reason for the decline of resistance to infection in patients with nephrotic syndrome is due to the loss of large amounts of IgG in the urine. The deficiency of B factor (the component of complement alternative pathway) leads to the defect of the immune modulation of bacteria. When malnutrition occurs, the nonspecific immune response of the organism is weakened and the immune function of the organism is impaired. Transferrin and zinc are lost in large quantities from urine. Transferrin is necessary for the maintenance of normal lymphocyte function, and the concentration of zinc ion is related to thymosin synthesis. Local factor. Pleural effusion, ascites, high skin edema caused by skin rupture and severe edema, local body fluid factor dilution, defensive function weakened, are all susceptible factors of nephrotic syndrome patients. Prior to the advent of antibiotics, bacterial infections were one of the leading causes of death in patients with nephrotic syndrome. Severe infections occurred mainly in children and the elderly, and adults were rare. The common clinical infection: primary peritonitis, cellulitis, respiratory tract infection and urinary tract infection. Once the infection is diagnosed, immediate treatment should be given. Hypercoagulable state and venous thrombosis nephrotic syndrome have hypercoagulable state, mainly due to the change of coagulation factor in blood. Including IX, Xi and VIII factor decreased, V, factor X, fibrinogen, beta thromboglobulin and platelet levels increased. Adhesion and aggregation of platelets are enhanced. Antithrombin III and plasmin activity decreased. Therefore, the in