第十章 代谢总论--王镜岩《生物化学》第三版笔记(完美打印版)（The tenth chapter, metabolism general - Wangs biochemistry third edition notebook (perfect print edition)）.docVIP

第十章 代谢总论--王镜岩《生物化学》第三版笔记(完美打印版)（The tenth chapter, metabolism general - Wangs biochemistry third edition notebook (perfect print edition)） The tenth chapter is the metabolism The first section is an overview I. definitions Metabolism (metabolism), also known as metabolism, is a general term for all chemical changes in the organism. Metabolism is the basic characteristic of life. Metabolism including anabolism and catabolism, the former is also called assimilation, refers to the body from the intake of nutrients in the environment, put them into their own material; the latter is also called dissimilation, refers to the body of the material into metabolites excreted. The two complement each other, and their balance enables the organism to maintain its stability and renew itself to adapt itself to the environment. Two, metabolic pathway Metabolic processes are accomplished by a series of enzymatic reactions. A group of enzymes linked to each other to complete a metabolic process known as metabolic pathways. Metabolic pathways have the following characteristics: 1., there is no fully reversible metabolic pathway. The synthesis and decomposition of substances, some completely different two metabolic pathways (such as fatty acid metabolism); some are partly through irreversible irreversible reactions (such as sugar metabolism). 2. the metabolic pathways are diverse in form, linear, branched, and annular. The 3. metabolic pathway has definite cellular localization. Enzymes have a definite distribution in the cell, so each metabolic process occurs in defined regions. For example, glycolysis in the cytoplasm, three carboxylic acid cycle in the mitochondrial matrix, oxidative phosphorylation in mitochondria. 4. metabolic pathways are communicated with each other. Each metabolic pathway may intersect one another through a common intermediate metabolite, and may also be interconnected by transition steps. Thus, various metabolic pathways are linked to form a complex metabolic n