第四十二章四环素类及氯霉素类（The forty-second chapter, tetracyclines and chloramphenicol）.docVIP

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第四十二章四环素类及氯霉素类（The forty-second chapter, tetracyclines and chloramphenicol）.doc

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第四十二章四环素类及氯霉素类（The forty-second chapter, tetracyclines and chloramphenicol）

第四十二章四环素类及氯霉素类（The forty-second chapter, tetracyclines and chloramphenicol） The forty-second chapter, tetracyclines and chloramphenicol Basic Requirements Key and difficult points Teaching hours Synopsis 1 basic requirements [TOP] 1.1 the antibacterial spectrum, antibacterial mechanism and clinical application of tetracycline, the in vivo process, adverse reaction of chloramphenicol, the antibacterial spectrum, antibacterial mechanism, clinical application and adverse reaction of chloramphenicol. 1.2 familiar with the characteristics of doxycycline and minocycline. 1.3 to understand the concept of broad-spectrum antibiotics, the classification of tetracyclines, and the characteristics of other drugs. 2 key and difficult [TOP] 2.1 key Antimicrobial spectrum, antibacterial mechanism, clinical application and main adverse reactions of the drugs. 2.2 difficulties The mechanism of antimicrobial action, the characteristics of each drug and the important adverse reactions 3 teaching hours [TOP] Recommendation 1.5 hours 4 Summary [TOP], Section 1, section second 4.1 section 1 tetracyclines [TOP] Tetracycline (tetracyclines) is a broad-spectrum antibiotic, with rapid inhibitory effect of gram positive bacteria and gram negative bacteria, but also has strong inhibitory effect on mycoplasma, chlamydia, Rickettsia, spirochetes and some protozoa. 4.1.1 drug classification Tetracycline (tetracycline), oxytetracycline (terramycin), chlortetracycline (chlortetracycline) and demeclocycline (demeclocycline) is a natural tetracycline; methacycline (methacycline) and doxycycline (doxycycline) and minocycline (minocycline) is a semi synthetic tetracycline. Antibacterial action characteristics of 4.1.2 It is a fast antibacterial, antibacterial activity of minocycline, doxycycline, cyclophilin, tetracycline, oxytetracycline. Tetracycline is no longer the first choice for this class of drugs. Oxytetracycline can still be used for treatment of intestinal amebiasis, curative effect is bette