morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria a randomised trial从儿童疟疾发病率年之后他们收到了间歇性预防治疗疟疾的随机试验.pdfVIP
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morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria a randomised trial从儿童疟疾发病率年之后他们收到了间歇性预防治疗疟疾的随机试验
Morbidity from Malaria in Children in the Year after They Had Received Intermittent Preventive Treatment of Malaria: A Randomised Trial ´ 1 1 ´ 1 1 ´ 1 Amadou T. Konate , Jean Baptiste Yaro , Amidou Z. Ouedraogo , Amidou Diarra , Adama Gansane , 1 ´ 1 ´ 1 ´ ´ 1 ´ 1 Issiaka Soulama , David T. Kangoye , Youssouf Kabore , Esperance Ouedraogo , Alphonse Ouedraogo , 1 ´ 1 2 3 2 Alfred B. Tiono , Issa N. Ouedraogo , Daniel Chandramohan , Simon Cousens , Paul J. Milligan , 1 2 2 Sodiomon B. Sirima , Brian M. Greenwood , Diadier A. Diallo * 1 Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Ouagadougou, Burkina Faso, 2 Department of Disease Control, London School of Hygiene and Tropical Medicine (LSHTM), London, United Kingdom, 3 Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom Abstract Background: Interventions that reduce exposure to malaria infection may lead to delayed malaria morbidity and mortality. We investigated whether intermittent preventive treatment of malaria in children (IPTc) was associated with an increase in the incidence of malaria after cessation of the intervention. Methods: An individually randomised, trial of IPTc, comparing three courses of sulphadoxine pyrimethamine (SP) plus amodiaquine (AQ) with placebos was implemented in children aged 3–59 months
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