identification of an abbreviated test battery for detection of hiv-associated neurocognitive impairment in an early-managed hiv-infected cohort识别一个简短的测试电池检测艾滋病毒相关神经认知障碍的early-managed艾滋病感染人群.pdfVIP

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2017-09-01 发布于上海
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identification of an abbreviated test battery for detection of hiv-associated neurocognitive impairment in an early-managed hiv-infected cohort识别一个简短的测试电池检测艾滋病毒相关神经认知障碍的early-managed艾滋病感染人群.pdf

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identification of an abbreviated test battery for detection of hiv-associated neurocognitive impairment in an early-managed hiv-infected cohort识别一个简短的测试电池检测艾滋病毒相关神经认知障碍的early-managed艾滋病感染人群

Identification of an Abbreviated Test Battery for Detection of HIV-Associated Neurocognitive Impairment in an Early-Managed HIV-Infected Cohort 1 2,3 2,3 1 3,4,5 David J. Moore *, Mollie J. P. Roediger , Lynn E. Eberly , Kaitlin Blackstone , Braden Hale , 3,6 3,7 3 1 3,4,5 Amy Weintrob , Anuradha Ganesan , Brian K. Agan , Scott L. Letendre , Nancy F. Crum-Cianflone 1 HIV Neurobehavioral Research Program, San Diego, California, United States of America, 2 Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota, United States of America, 3 Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America, 4 HIV Clinic, Naval Medical Center San Diego, San Diego, California, United States of America, 5 Naval Health Research Center, San Diego, California, United States of America, 6 Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America, 7 Infectious Disease Clinic, National Naval Medical Center, Bethesda, Maryland, United States of America Abstract Background: HIV-associated neurocognitive disorders (HAND) remain prevalent despite improved antiretroviral treatment (ART), and it is essential to have a sensitive and specific HAND screening tool. Methods: Participants were 200 HIV-infected US military beneficiaries, managed early in the course of HIV infection, had few comorbidities, and had open access to ART. Participants completed a comprehensive, sev