有哪些信誉好的足球投注网站identification and comparative expression analysis of interleukin 215 receptor β chain in chickens infected with e. tenella识别和比较分析215年白介素受体表达在鸡感染大肠tenellaβ链.pdfVIP
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identification and comparative expression analysis of interleukin 215 receptor β chain in chickens infected with e. tenella识别和比较分析215年白介素受体表达在鸡感染大肠tenellaβ链
Identification and Comparative Expression Analysis of Interleukin 2/15 Receptor b Chain in Chickens Infected with E. tenella 1 1 1 1 1 1 Jipseol Jeong , Woo H. Kim , Jeongmi Yoo , Changhwan Lee , Suk Kim , Jae-Hyeon Cho , Hyung- 2 3 4 1 Kwan Jang , Dong W. Kim , Hyun S. Lillehoj , Wongi Min * 1 College of Veterinary Medicine and Research Institute of Life Science, Gyeongsang National University, Jinju, Korea, 2 Departments of Infectious Diseases and Avian Diseases, College of Veterinary Medicine and Korea Zoonosis Research Institute, Chonbuk National University, Jeonju, Korea, 3 National Institute of Animal Science, RDA, Cheonan, Chungnam, Korea, 4 Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America Abstract Background: Interleukin (IL) 2 and IL15 receptor b chain (IL2/15Rb, CD122) play critical roles in signal transduction for the biological activities of IL2 and IL15. Increased knowledge of non-mammalian IL2/15Rb will enhance the understanding of IL2 and IL15 functions. Methology/Principal Findings: Chicken IL2/15Rb (chIL2/15Rb) cDNA was cloned using 59/3 9-RACE. The predicted protein sequence contained 576 amino acids and typical features of the type-I cytokine receptor family. COS-7 cells transfected with chIL2/15Rb produced proteins of approximately 75 and 62.5 kDa under normal and tunicamycin-treated conditions, respectively. The genomic structure of chIL2/15Rb was similar to its mammalian counterparts. chIL2/15Rb transcripts were detected in the lymphoblast cell line CU205 and i
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