hookworm “the great infection of mankind”钩虫感染u201c伟大的人类u201d.pdfVIP

Open access, freely available online Neglected Diseases Hookworm: “The Great Infection of Mankind” Peter J. Hotez*, Jeff Bethony, Maria Elena Bottazzi, Simon Brooker, Paulo Buss Introduction hookworm infection. However, based on an extensive In 1962, Norman Stoll, the distinguished Rockefeller Institute search of the literature since 1990, the worldwide number scientist who helped to establish human parasitology research of cases of hookworm was recently estimated to be 740 in North America, described the unique health impact of million people [4]. The highest prevalence of hookworm hookworm as follows [1]: occurs in sub-Saharan Africa and eastern Asia (Figure 1). As it was when I fi rst saw it, so it is now, one of the most evil High transmission (defi ned below) also occurs in other of infections. Not with dramatic pathology as are fi lariasis, or areas of rural poverty in the tropics, including southern schistosomiasis, but with damage silent and insidious. Now that China [5], the Indian subcontinent [6], and the Americas malaria is being pushed back hookworm remains the great [7]. In all regions, there is a striking relationship between infection of mankind. In my view it outranks all other worm hookworm prevalence and low socioeconomic status (Figure infections of man combined…in its production, frequently 2) [4]. Hookworm’s neglected status partly refl ects its unrealized, of human misery, debility, and ineffi ciency in the concentration among the world’s poorest 2.7 bil