heart rate variability characteristics in sedentary postmenopausal women following six months of exercise training the drew study心率变异性特征在久坐不动的绝经后妇女以下六个月的运动训练研究.pdfVIP

Heart Rate Variability Characteristics in Sedentary Postmenopausal Women Following Six Months of Exercise Training: The DREW Study 1 2 3,4 1 Conrad P. Earnest *, Carl J. Lavie , Steven N. Blair , Timothy S. Church 1 Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States of America, 2 Department of Cardiology, Ochsner Health System, New Orleans, Louisiana, United States of America, 3 Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America, 4 The University of North Texas, Denton, Texas, United States of America Abstract Background: Decreased heart rate variability (HRV) is associated with a higher risk of mortality. Overall, postmenopausal women have lower levels of HRV than premenopausal women, which may be additionally complicated by lifestyle related behaviors such as physical inactivity and obesity. Though cardiorespiratory exercise training increases HRV, little is known regarding the exercise dose necessary to promote this improvement. Methodology/Principal Findings: Our primary aim was to measure HRV in post-menopausal women following 6-months of exercise training. We examined supine resting HRV in 373 post-menopausal women (45–75 y) after 6-months of randomly assigned and double-blinded administered exercise training exercise training at 50%, 100% and 150% of the NIH Consensus Development Panel’s recommended minimal physical activity level. This corresponded to 4, 8, or 12 kcal/kg per week (KKW) of energy expenditure. At baseline, we observed no significant differences in HRV or hormone replacement use between treatment groups. However, we did observe that Caucasian women and those taking ant