a novel and efficient gene transfer strategy reduces glial reactivity and improves neuronal survival and axonal growth in vitro新颖和有效的基因转移策略减少胶质反应性,提高体外神经元存活和轴突生长.pdfVIP
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a novel and efficient gene transfer strategy reduces glial reactivity and improves neuronal survival and axonal growth in vitro新颖和有效的基因转移策略减少胶质反应性,提高体外神经元存活和轴突生长
A Novel and Efficient Gene Transfer Strategy Reduces Glial Reactivity and Improves Neuronal Survival and Axonal Growth In Vitro 1 2 1 1 3 Mathieu Desclaux , Marisa Teigell , Lahouari Amar , Roland Vogel , Minerva Gimenez y Ribotta , Alain Privat4*, Jacques Mallet1 1 Biotechnology and Biotherapy, Centre de Recherche de l’Institut du Cerveau et de la Moelle Epiniere, Centre National de la Recherche Scientifique (CNRS) UMR 7225, ´ ´ ´ ˆ ´ ˆ ` Institut National de la Sante et de la Recherche Medicale (INSERM) UMRS 975, Universite Pierre et Marie Curie (UPMC) - Hopital de la Pitie Salpetriere, Paris, France, ´ ´ 2 NEUREVA-inc., Montpellier, France, 3 Consejo Superior de Investigationes Cientifıcas (CSIC), Universidad Miguel Hernandez (UMH), Instituto de Neurociencias de ˜ ´ ´ ´ ´ Alicante, Sant Joan D’Alacant Nacional, Espana, 4 Institut National de la Sante et de la Recherche Medicale (INSERM) U583, Physiopathologie et Therapie des Deficits ´ Sensoriels et Moteurs, Institut des Neurosciences de Montpellier (INM), Universite Montpellier 2, Montpellier, France Abstract Background: The lack of axonal regeneration in the central nervous system is at
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