Q开关Nd-YAG激光治疗颧部褐青色痣280例.docVIP

Q开关Nd:YAG激光治疗颧部褐青色痣280例[摘要]目的：观察Q开关Nd：YAG激光治疗颧部褐青色痣的临床疗效及不良反应。方法：应用Q开关Nd：YAG激光治疗280例患者，波长为1064nm，光斑直径3～4mm，能量密度9～11J/cm2，脉宽10ns。术后3～6个月复诊，根据术前术后照片判定疗效，标准分为Ⅳ级。结果：治疗1～5次，间隔时间3～12个月，共治愈107例（38.2%），平均治疗次数2.7次，总有效率77.9%，疗效与治疗次数成正相关。术后色素沉着152例（54.3%）。结论：Q开关Nd：YAG激光治疗颧部褐青色痣效果满意，虽然术后色素沉着发生率较高，但均能随时间逐渐消退，未见其他不良反应及并发症。 [关键词]颧部褐青色痣；Q开关Nd：YAG激光；疗效 [中图分类号]R758.51 [文献标识码]A [文章编号]1008-6455（2008）06-0898-02 Efficacy of Q-switched Nd：YAG laser on 280 cases of naevus fuscocaeruleus zygomaticus TENG Wen,WANG Min,LI Shao-hua,ZHANG Miao-bo,REN Li-hong （Department of Plastic and Aesthetic, 2nd affiliated hospital, Harbin Medical University ,Harbin 150086, Heilongjiang,China） Abstract：ObjectiveTo observe the therapeutic effect and side effect of Q-switched Nd:YAG laser irradiation on naevus fuscocaeruleus zygomaticus(NFZ).MethodsA total of 280 cases were treated with 1 064nm wave length laser.The diameter of therapy spot was 3～4mm, pulse duration was 10ns,and energy density was 9～11 J/cm2. The therapeutic effect was judged according photograph took before treatment and 3～6 months after treatment. The judgment standards of therapeutic effect were classified into Ⅳ grades. Results The therapeutic times ranged from 1～5.The interval of therapy was 3～12 months.107 cases（38.2%） were cured, and the average times of cure were 2.7.The total effective rate was 77.9%, and the therapeutic effect was positively related with therapeutic times.Hyperpigmentation was observed in 152 cases（54.3%）.ConclusionQ-switched Nd:YAG laser has fairly good therapeutic effect on naevus fuscocaeruleus zygomaticus.There is almost no other side effect except the high occurring of hyperpigmentaion,and it is cleaned up slowly. Key words：naevus fuscocaeruleus zygomaticus(NFZ);Q-switched Nd:YAG laser;therapeutic effect 颧部褐青色痣是临床常见的一种真皮色素增加性疾病，好发于中青年女性，影响面部容貌。2001年3月～2008年1月，我们应用Q开关Nd：YAG激光治疗280例颧部褐青色痣患者，取得了满意效果，现报道如下。 1临床资料和方法 1.1 一般资料：280例患者均来自我科门诊，其中男4例，女276例，年龄23～48岁，平均为35岁，病史2～16年。发病部位：单纯双侧颧颞