单相双相障碍患者应对方式比较.docVIP

双相障碍患者 【摘要】目的 探讨双相障碍患者的情感气质特征，并进一步分析情感气质特征与双相障碍的关联。方法 采用横断面的病例对照设计，应用气质评定量表(Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version，TEMPS-A)评估被试的情感气质。共入组双相障碍患者144例，复发性抑郁症患者189例，正常对照123例。用单因素方差分析、t检验、非参数检验、logistic回归分析等进行统计分析。结果TEMPS-A的5个因子分在双相障碍组与对照组、复发性抑郁症组与对照组之间的差异均有统计学意义，但在双相障碍组与复发性抑郁症组之间，仅情感旺盛气质的差异有统计学意义（Z= -2.967，P=0.003）。进一步做logistic回归分析，情感旺盛气质进入最终的回归方程，其OR值是1.119，95%CI[1.009，1.242]，该模型对双相障碍的预测准确率是67.7%。结论 双相障碍患者可能具有更多的病理性情感气质，其中情感旺盛气质可能是双相障碍的特征性情感气质，在考虑了疾病状态的影响后，仍可在一定程度上增加个体患双相障碍的风险。 【关键词】双相障碍 情感气质 TEMPS-A 情感旺盛气质 The Specific Affective Temperaments of Patients with Bipolar Disorder YUAN Chengmei, HUANG Jia , LI Zezhi, SU Yousong, FANG Yiru (Divisions of Mood Disorder, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China. [Abstract] Objective: To expolor the specific affective temperaments of patients with bipolar disorder and the association between bipolar disorder and affective temperaments. Methods: The study was designed as a cross-sectional case-control study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version(TEMPS-A) was used to evaluate the affective temperaments of all the samples. One hundred and forty four patients with bipolar disorder, 189 patients with recurrent depression and 123 controls were included in the study. ANOVA, t-Test, Mann-Whitney Test and Logistic regression were used for data analysis. Results: Compared to controls, both patients with bipolar disorder and recurrent depression scored significantly higher in all the five affective temperaments. However, only hyperthymic temperament scored significantly higher in patients with bipolar disorder compared to patients with recurrent depression（Z= -2.967，P=0.003）. In the further Logistic analysis, controlled the effect of disease status, hyperthymic temperament was associated with bipolar disorder. The OR was 1.119，95%CI[1.009，1.242] and the predictive rates of Log