高血压患者血压变异性与脉搏波传导速度的关系.PDFVIP

华西医学 2017 年 6 月第 32 卷第 6 期 • 847 •   ·论 著· 高血压患者血压变异性与脉搏波 传导速度的关系 蔡亚丽，王斯，张鑫，朱小江，刘琦，张强，陈晓平 四川大学华西医院心脏内科（成都  610041 ） 【摘要】   目的     比较不同的血压变异性与血管硬化程度的关系，探讨高血压患者日常监测血压更优的方 式。方法    通过选择 2011 年 9 月—2014 年 3 月对成都市武侯区晋阳社区 140 例高血压患者进行人口学资料收集、 行生物化学、肱-踝脉搏波传导速度（brachial-ankle pulse wave velocity ，baPWV ）等检查，指导患者规范行家庭血压 自我监测及诊室血压测量。收集相关数据，进行统计学分析，比较几种血压变异性和脉搏波传导速度的关系。 结果    晨起短时家庭血压变异性与 baPWV 呈正相关（r=0.313，P=0.011），睡前短时家庭血压变异性与 baPWV 呈 正相关（r=0.241，P=0.042），天与天间血压变异性与 baPWV 呈正相关（r=0.269，P=0.030）。月与月间血压变异性、 短时诊室血压变异性与 baPWV 的关系无统计学意义（P0.05）。结论    在高血压患者血压变异性的监测中，家庭 血压变异性的监测优于诊室血压变异性的监测，且晨起监测优于夜间监测。 【关键词】  家庭自测血压；血压变异性；原发性高血压；脉搏波传导速度 Relationship between blood pressure variability and pulse wave velocity in patients with hypertension CAI Yali, WANG Si, ZHANG Xin, Zhu Xiaojiang, LIU qi, Zhang Qiang, Chen Xiaoping Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China Corresponding author: Chen Xiaoping, Email: xiaopingchen11@126.com 【Abstract 】 Objectives    To explore the best mode of blood pressure monitoring by comparing the correlation of deferent kinds of blood pressure variability with arterial stiffness. Methods    This study was conducted among 140 hypertensive patients in Wuhou Strict, Chengdu. Baseline data was collected including demographic data, biochemical examination and brachial-ankle pulse wave velocity (baPWV) measurement and so on. A consecutive home blood pressure was also gained by the individuals themselves and the clinical blood pressure was also recorded during the visit. The correlation between baPWV and the blood pressure variability were tested. Results     The blood pressure variability measured at home in the mor