激素+内毒素-Effect of lipopolysaccharide (LPS) on mouse model of steroid-induced avascular necrosis in the femoral head ANFH.pdfVIP

J. Microbiol. Biotechnol. (2014), 24(3), 394–400 Research Article /10.4014/jmb.1311.11057 jmb Effect of Lipopolysaccharide (LPS) on Mouse Model of Steroid-Induced Avascular Necrosis in the Femoral Head (ANFH) 1† 2† 1† 1 1 1 1 Soyoon Ryoo , Sukha Lee , Seunghyun Jo , Siyoung Lee , Areum Kwak , Eunsom Kim , Jongho Lee , Jaewoo Hong1 1 3 2 1* 2* , Hyunjhung Jhun , Youngmin Lee , Anshul Shyam Sobti , Soohyun Kim , and Kwang-Jun Oh 1 2 Laboratory of Cytokine Immunology, Department Biomedical Sciences and Technology, and Department of Orthopaedic Surgery, School of Medicine, Konkuk University, Seoul 143-701, Republic of Korea 3Department of Medicine, Pusan Paik Hospital, Collage of Medicine, Inje University, Busan 633-165, Republic of Korea Received: November 19, 2013 Revised: November 28, 2013 Avascular necrosis of the femoral head (ANFH) is commonly observed in patients treated with Accepted: November 29, 2013 excessive glucocorticoid (GC). Single administration of lipopolysaccharide (LPS) has shown to First published online induce immune stimulatory factors. However, the effect of repeated administration of LPS on December 3, 2013 GC-induced ANFH has not been studied. Thus, the purpose of this study was (i) to examine *Corresponding authors