Signal sensorysystems that impactr54-dependenttranscription:(信号sensorysystems impactr54-dependenttranscription).pdfVIP
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Signal sensorysystems that impactr54-dependenttranscription:(信号sensorysystems impactr54-dependenttranscription)
R E V I E W A R T I C L E Signal sensory systems that impact r54-dependent transcription Victoria Shingler ˚ ˚ Department of Molecular Biology, Umea University, Umea, Sweden Correspondence: Victoria Shingler, Abstract ˚ Department of Molecular Biology, Umea ˚ Alternative s-factors of bacteria bind core RNA polymerase to program the University, 901 87 Umea, Sweden. Tel.: 146 90 852 534; fax: 146 90 772 630; e-mail: specific promoter selectivity of the holoenzyme. Signal-responsive changes in the victoria.shingler@molbiol.umu.se availability of different s-factors redistribute the RNA polymerase among the distinct promoter classes in the genome for appropriate adaptive, developmental Received 6 July 2010; revised 30 September and survival responses. The s54-factor is structurally and functionally distinct D 2010; accepted 2 October 2010. 54 from all other s-factors. Consequently, binding of s to RNA polymerase confers o Final version published online 5 November 2010. w uniq
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