胶团超滤法制备丹参注射液.pdfVIP

200 3 6 中成 药 June, 2003 25 6 Chinese T radi io nal Pa en M edicine Vol . 25 N o. 6 [ ] 胶团超滤法制备丹参注射液 1 2 1 1 1 王 丹, 龚 涛, 孙 冰, 李 莉, 付芳敏 ( 1. 华西医科大学制药厂, 四 成都610041; 2 . 四 大学华西药学院, 四 成都6 1004 1) : ; ; - 80; : : ( ) : -80 , 50000 , : : R944 . 1+ 1 : A : 1001- 1528( 2003) 06- 044 1- 0 3 Study on preparing Danshen Injection by micelle-ultrafiltration 1 2 1 1 1 WA N G Dan , GON G T ao , SU N Bing , L I L i , FU Fang- min ( 1 . The Phar maceutical Factory of West China Medical University , Chengdu 6100 1 China; 2. West China School of Pharmacy, S ichuan Uni- versity , Chengdu 6100 1, China) Key words: Danshen Injec ion; micelle- ul raf il ra ion ; T ween- 80; pro oca echualdehy de Abstract: Objective: T o prepare Danshen Injec ion ( Radix Salviae Mil iorrhizae) by m icelle- ul raf il ra ion. Methods: F or preparing Danshen Injec ion, w e packed he impuri ies in he m acrofil ered liquor of Radix Salviae M il iorrhizae wi h m icelle of T ween- 80 , and ul rafil ered he compounds w i h ul rafil ra ion membrane w i h- holding molecular w eigh more han 50000. T hen w e evalua ed he process w i h he comprehensive indexes in- cluding loss ra e of UV absorbance, loss ra e of Pro oca echualdehyde and he s abili y of ransparence. onclu- sion: T he process of Danshen Injec ion prepared by micelle- ul rafil ra ion is be er han ha of ordinary ul rafi-l ra ion . , , , - 80 , - 80 , [ 1] , , [ 2] , , 1 1. 1 仪器 ( )