炔酯的制备z460292_s.pdfVIP

Supporting Information for Angew. Chem. Int. Ed. 200460292 © Wiley-VCH 2004 69451 Weinheim, Germany Dramatic Enhancement of Catalytic Activity in Ionic Liquid: Highly Practical Metal Triflates-Catalyzed Friedel-Crafts Alkenylation of Arenes with Alkynes in an Ionic Liquid Choong Eui Song,* Da-un Jung, Su Yhen Choung, Eun Joo Roh, Sang-gi Lee* Prof. Choong Eui Song, Su Yhen Choung, Institute of Basic Science, Department of Chemistry, Sungkyunkwan University, 300 chunchun, Jangan, Suwon, Kyunggi, 440- 746, Korea, TEL: +82 31 290 7064, FAX: +82 31 290 7075, E-mail: s1673@skku.edu Da-un Jung, Dr. Eun Joo Roh, Dr. Sang-gi Lee, Life Sciences Division, Korea Institute of Science and Technology, PO Box 131, Cheongryang, Seoul 130-650, Korea. E-mail: sanggi@kist.re.kr General. All reactions were performed in nitrogen atmosphere using standard schlenk techniques. Chromatographic purification of products was carried out by flash chromatography using Merck silica gel 60 (230-400 mesh). Thin layer chromatography was carried out on Merck silica gel 60F plates. 1H NMR (300 MHz) and 13C NMR (75.0 MHz) spectra were recorded on a Brucker-Spectrospin 300 spectrometer using TMS as an internal standard. GC-MS analysis were performed using GC/MSD; HP 5890. Materials. All metal triflates used in this study were purchased from Aldrich. Ionic liquids used in this study were nearly chloride-free (10 ppm) and their water content was ca. 200-300 ppm (determined by Karl-Fisher titration). Other organic solvent (methylcyclohexane) was distilled prior to used. All chemicals were obtained from commercial sources and used without further purification. Aryl 3-substituted propiolates and alkynalides were prepared according to the following procedure. R