塑料中内分泌干扰物的含量检测与来源分析(原).docxVIP

Chemical Analysis of Endocrine Disrupting Compounds of Food packaging Plastic FilmChongxing Huang*, Wen Lin, Cuicui Li, Dongjie Xue（College of Light Industry Food Engineering, Guangxi University, Nanning, 530004, China）摘要：Contamination of foodstuffs by environmental pollutants receives much attention. Until recently, food packaging as a source of xenobiotics, especially those with endocrine disrupting properties, has received little awareness despite its ubiquitous use. This study presents the research on the analysis of endocrine disrupting compounds, DEA, DBP, BBP, DEHA,DEHP, BHT, BHA,BP and MBP of4 common used composite packaging films in food-contacted, which belongedplasticizer, Antioxidant，UV?absorber.In the chemical analysis, composite films were extracted by acetone under ultrasonic condition, and analysis by gas chromatography/mass spectrometry. The sources of the 9 endocrine disrupting compounds were analysis and its content were compared with the related laws and regulations. 研究结果表明，四种塑料中除了DEHA没有检出外，其他组分都有检测到. 并且,这些组分在塑料基材和油墨中都有分布，说明它们都是常用的添加剂，在树脂成型和油墨印刷中都发挥作用。DBP在未印刷的四种塑料薄膜样品中的含量是15.67-20.73 ug/g，在印刷后的四种塑料薄膜样品中的含量是25.60-38.90 ug/g。BBP在未印刷的四种塑料薄膜样品中的含量是14.26-20.83 ug/g，而在印刷后的四种塑料薄膜样品中的含量是17.72-29.97 ug/g。DEHP未印刷的四种塑料薄膜样品中的含量是165.91-226.38 ug/g, 在印刷后的四种塑料薄膜样品中的含量是298.36-369.88 ug/g. BHT在未印刷的四种塑料薄膜样品中的含量是6.26-7.98 ug/g，在印刷后的四种塑料薄膜样品中的含量是10.11-10.26 ug/g。BHA在未印刷的四种塑料薄膜样品中的含量是157.93-213.27 ug/g，在印刷后的四种塑料薄膜样品中的含量是201.97-326.56. BP在未印刷的四种塑料薄膜样品中的含量是0.78-1.17 ug/g，在印刷后的四种塑料薄膜样品中的含量是2.58-2.81 ug/g. MBP在未印刷的四种塑料薄膜样品中的含量是4.12-5.82 ug/g，在印刷后的四种塑料薄膜样品中的含量是6.56-8.86 ug/g。在所有的8种未印刷和印刷后的样品中，除了DEHA在所有的样品中没有被检出以外， Larger amount of EDCs were found in printed products than unprinted products.将检测结果与欧盟标准EU 10-2011中相关规定进行对比发现，塑料样品中相关物质的含量都在规定范围内。关键词：内分泌干扰物；复合包装薄膜，气相色谱-质谱联用INTRODUCTION环境内分泌干扰物（Endocrine Disrupting Chemicals, EDCs）是一类广泛分布于环境和食物、包装、玩具等各类消费品中的可以对人体内激素含量产生影响的物质[,][]，是一种外源性干扰人体内分泌系统的化学物质，它们通过逐步摄入、积累等途径，而不是直接作为有毒有害物质给生物体带来不利影响，像雌激素类物质那样对生物体产生作用，即使数量微少，也可能让生物体的内分泌系