Study on the physiological function and application of γ―aminobutyric acid and its receptors.docVIP
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Study on the physiological function and application of γ―aminobutyric acid and its receptors.doc
Study on the physiological function and application of γ―aminobutyric acid and its receptors Abstract:γ-aminobutyric acid(GABA)is a functional non protein amino acid,which is widely distributed in animals and plants,in many kinds of metabolic activities,physiological activity is very high.In the animal,as an important inhibitory neurotransmitter,GABA concentration in nerve tissue,and the content in the brain tissue of about 0.1-0.6mg/ grams.With the gradual deepening of GABA research,GABA has been more and more widely used in food,animal husbandry and other industries.This paper mainly analyzes the physiological function of GABA and its receptor,and its application is also discussed for our referenc. Keywords:γ-aminobutyric acid;γ-aminobutyric acid receptor;physiological function 1 Introduction γ-aminobutyric acid(GABAB)is known as aminobutyric acid,which is an important inhibitory neurotransmitter.About 50% of the central synaptic site is GABA as a transmitter,to regulate the body function.There are 3 subtypes of GABA receptor,namely,GABAA receptor,GABAB receptor and GABAC receptor.GABAB receptor is a kind of metabolic receptor,GABAA receptor and GABAC receptor are ionic receptor,which plays a key role in the central nervous system and peripheral tissues,which can regulate autism,depression,epilepsy and mental disorders,such as mental disorders,and can also be used as feed additive to alleviate the harm caused by the stress response to animal husbandry.Therefore,it is very important to study GABA and its receptors. 2 Physiological characteristics of GABA and its receptors 2.1 Physiological characteristics of GABA GABA sub type is C4H9NO2,Sub sub quality of 103.12u,which is widely distributed in animals,plants and microorganisms,the highest concentration of mammalian brain tissue,mainly distributed in the thalamus,hippocampus,basal ganglia and other regions.It can reduce the cell metabolism and the activity of neurons,reduce the influx of io
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