Limited Diagnostic Value of Routine Screening of Neonates with the Urinary Group B Streptococcal Antigen Tests》.pdfVIP
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Limited Diagnostic Value of Routine Screening of Neonates with the Urinary Group B Streptococcal Antigen Tests》.pdf
Pediatrics and Neonatology (2014) 55, 480e486 Available online at ScienceDirect journal homepage: ORIGINAL ARTICLE Limited Diagnostic Value of Routine Screening of Neonates with the Urinary Group B Streptococcal Antigen Tests Kai-Hsiang Hsu a, Ming-Chou Chiang a,b,*, Reyin Lien a, Peng-Hong Yang a, Shih-Ming Chu a, Jen-Fu Hsu a, Ren-Huei Fu a a Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan b Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan Received Dec 8, 2013; received in revised form Feb 7, 2014; accepted Mar 13, 2014 Available online 21 July 2014 Key Words Background: A urinary latex test for detection of antigens from group B Streptococcus (GBS) antigen test; has been used for the diagnosis of invasive GBS disease. However, the value of routine bacteremia; screening of infants with this test has not been determined. group B Methods: All infants admitted to Linkou Chang-Gung Memorial Hospital (Taoyuan, Taiwan) streptococcus; from January 2005 to May 2013 were screened with a urinary GBS antigen test (Wellcogen Strep infant; B). Medical records were retrospectively reviewed to determine the diagnostic value of this screening; test. meningitis Results: A total of 14,277 infants were tested and 38 cases had confirmed diagnoses of invasive GBS disease (34 bacteremia, 18 meningitis, 14 both), corresponding to a prevalence of 0.27% among our admitted infants. A total of 106 infants had po
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