重症监护病房下呼吸道感染的病原学分析及对策.pdfVIP

2007 28 5 405 王建斌 金先银 何 军 [ ] ( ICU) , ICU 1120 ; B ( ESBLs) ; 39 , ICU 4 1% ~ 72. 9% ; ESBLs 60% 64% ; 56% ICU , , ; , [ ] ; B ; ; Analysis and strategy of pathogenic bacteria of lower respiratory infection in I CU Wang J ianbin, J in X iany ing , H e J un Dep ar tment of I C U, H uaibe i P eop le s H osp ital , H ua ibei 235000 [Abstract] Obj ective T o i vestigat e the drug resista ce situatio to commo ly used a tibiot ics of pathoge ic bacte- ria w hich w as from the ICU of our hospital, a d compared the coi cide ce of bro chofibroscope sampli gs a d routi e sampli gs. Methods Taki g agar gel diffusio test to determi e the 1120 strai s of pathoge ic bacteriums; Taki g doub- le paper diffusio scree i g test to determi e exte ded spect rum B lactamases (ESBLs) of Escherichia coli a d Klebsiella p eumo iae; The results of 39 st rai s sam pli gs w ith bro chofibroscope compared w ith sam pli gs from rout i e met hod. Results The drug resista ce rate of commo ly used pathoge ic bacteria i ICU to the third ge eratio cephalospori is 41 ~ 72. 9% ; Detect able rate of ESBLs of Escherichia coli a d Klebsiella p eumo iae is separately 60% a d 64% ; T he coi - cide ce of bro chofibroscope sampli gs w ith rout i e sampli gs is 56% . Conclusion It is ecessary t o i te sively mo itor the drug resista ce of pathoge ic bacteria, ratio ally to use a tibiot ics, especially the third ge erat io cephalospori . Whe the therapeut ic effect is bad, shoud taki g bro chofibroscope to sample. [ Key words] ICU; ESBLs; Drug resista ce; Protected specime brush ( ICU ) ICU 48 , 256 , , , , , 1120 , 45