注射用丹参冻干抗人血小板聚集标准研究.pdfVIP

·565· 注射用丹参(冻干)抗人血小板聚集标准研究 张妹梅 (临沂市人民医院，山东临沂276003) 摘要：目的 以确定注射用丹参(冻干)对血小板聚集抑制率的限度标准为目的，确定血小板聚集率指标符合生产和临床 实际。方法 采集人血进行初步处理，将测定样品制成适宜浓度的溶液，将适宜用量的样品溶液和人血混合后测定血小板聚 集率，计算其血d、板聚集抑制率。进行重复性试验和重现性试验。确定血小板聚集抑制率限度标准。结果 本实验的注射用 丹参(冻干)对血小板聚集抑制率限度标准的下限为25．1士9．2。结论该试验提供的方法可行，可以确定小板聚集抑制率的 限度标准。 关键词：丹参；注射用丹参(冻干)；血小板；血小板聚集抑制率 中图分类号：R927．11文献标识码：A文章编号：1672—7738(2010)09—0565—03 on of rateSalviafor standard inhibitionof Study plateletaggregation Injection(1yophilized) ZHANGShu—mei of 276003) (People’8HospitalLinyi，Linyi ABSTRACT：OBJECTIVETodetermineSalviafor inhibitionratelimitsof Injection(1yophilized)onplateletaggregation thestandardforthe rate consistentwiththe andclinical purpose，determiningplateletaggregationtarget production prac。 tic已METHODSTocollectbloodanddo concentrationofsolutionwasmade sam— preliminaryprocessing。suitable byworking amountofthe solutionand bloodtOdetermine rateandcalculated ple，mixedappropriate sample people’s plateletaggregation inhibitionrate．Testfor and inhibition plateletaggregation repeatabilityreproducibilitytest．Determiningplateletaggregation stand— limitsofthestandardrate．RESULTSIdentificationof inhibitionof limitsofthe plateletaggregation plateletaggregation ardrateis25．1士9．2．CONCLUSIONThistestmethodwasfeasi