应用肥胖指标筛查成年男性动脉硬化的初步的研究.pdfVIP

2008 11 25 11 J Clin Res, Nov. 2008, Vol 25, 11 1937 论著 肖琼 陈化 田英 ( 中南大学湘雅二医院老年医学科, 湖南 长沙 410011) [ ]目的探讨应用体重指数( BM I) 腰围和腰臀比等肥胖指标筛查成年男性 脉硬化时的最佳切 点方法分析147 例成年男性的BM I腰围和腰臀比与颈股 脉脉搏波速( CFPWV) 之间的相互关系; 用 ROC 曲线确定腰围和腰臀比筛查 脉硬化( CFPWV 10) 时的最佳切点和参考切点, 并用ROC 曲线下面积 评价它们在筛查时的整体准确性结果 成年男性腰围腰臀比与 CFPWV 呈显著正相关( P 均 0.05) ; BMI 与 CFPWV 之间无显著相关性( P 0.05) ; ROC 曲线下面积显示在筛查成年男性有无 脉硬 化存在时腰臀比要比腰围更准确更有价值; 腰围腰臀比检出 脉硬化的最佳切点值分别为91. 5 cm 和 0. 93, 其诊断灵敏度分别为47% 和65% 特异度分别为83% 和69% ; 腰围的高灵敏度和高特异度参考切点 分别为77. 5 cm 和97. 5 cm,腰臀比的高灵敏度和高特异度参考切点分别为 0. 86 和 0. 97结论中心性肥 胖与 脉硬化密切相关,腰围91. 5 cm 和或腰臀比0. 93 可作筛查成年男性 脉硬化的最佳切点, 当腰围 和或腰臀比超过这两 个数值时应进一步行CFPWV 检查, 以排除大 脉硬化 [ ] 脉硬化; 肥胖症 Primary Investigation on Obese indexes for Screening Arteriosclerosis i n Male Adults X IA O Qiong , CH EN H ua, YIN G T ian ( Dep artment of Geratology , Secon X iangy a H osp ital, Central S outh University , Changsha 4 10011, China ) [Abstract]O jective T o explore the est and reference cutoff value of o ese indexes including ody mass index( BMI) , waist circumference ( WC) and waistt ohip ratio (WH R) for screening arteriosclerosis in male a dults. Methods A total of 147 male adults were included in this series. T hree o ese parameters including BMI, WC and WHR w ere invest igated in this study . The correlation etw een carotidfemoral pulse wave ve locit y ( CFPWV) and the o ese parameters w as analyzed y Pearson correlation test. ROC curve w as used t o determine t he est and reference cutoff value of the parameters. T heir conformity in predicting arteriosclerosis was analyzed y area under curve (AUC) . Results 1. Both WC and WH R showed a signif icantly positive correlation with CFPWV in adult male patients whose Pearson coefficients w ere 0. 245( P 0.05) and 0. 289 ( P 0. 05) , respectively . 2. AUC showed that WH R was ett er th