发酵法生产甲壳素纤维.pdfVIP

第 28 卷 　第 8 期 纺 　织 　学 　报 Vol. 28 　No. 8 2007 年 8 月 Journal of Textile Research Aug. 　2007 ( ) 文章编号 2007 发酵法生产甲壳素纤维 秦益民 ,朱长俊 (嘉兴学院 生化材料研发中心 ,浙江 嘉兴 　314001) 摘 　要 　为了找到一种可以大规模生产甲壳素的方法 ,研究了利用丝状真菌生产甲壳素纤维的发酵工艺。结果显 示犁头霉属真菌生产甲壳素的能力最高 ,每200 mL培养液中最多可提取200 mg 甲壳素。丝状真菌发酵后得到的甲 壳素为中空纤维状物质 ,其长度在 50～100 mm ,与纺织用纤维的长度基本相同。这种纤维经过处理后可以通过造 纸工艺直接加工成类似于水刺非织造布的结构。研究结果证明采用发酵法制备的甲壳素纤维具有很好的生物活 性 ,它们能吸附并结合细胞 ,加快细胞的繁殖 ,用做医用敷料可以有效地促进伤口的愈合。 关键词 　甲壳素纤维; 真菌 ; 发酵 ; 生物材料 中图分类号:TS101921 　　　文献标识码 :A 　　　 Production of chitin fibers by fermentation QIN Yimin ,ZHU Changjun ( The Biochemical Materials Research and Development Center , Jiaxing University , Jiaxing , Zhejiang 　314001 , China) Abstract 　In order to find out a mass production method of chitin , this paper studied the production process for chitin by using the fermentation of fungi. Results showed that Absidia fungi yields the highest volume of chitin , producing up to 200 mg chitin per 200 mL culture media. The chitin produced through the fermentation process takes the form of hollow fibers , with the length ranging from 50 to 100 mm , similar to that of textile fiber. After treatment , these fibers can be made into a structure similar to hydroentangled nonwoven by the paper making process. The research demonstrated that the chitin fiber made by fermentation has very good bioactivity , is bioadsorbable , and facilitates the growth of cell and accelerates wound healing when used as medical dressings. Key words 　chitin fiber ;fungi ;fermentation ;biomaterial 　　生物科技在纺织领域