解脲脲原体与人型支原体感染检测的临床意义及治疗.docVIP

解脲脲原体与人型支原体感染检测的临床意义及治疗 贵州省人民医院 中心实验室 贵阳 550002 蒲海 金婷婷 作者单位;550002 贵州省 贵州省人民医院 中心实验室 通讯作者：金婷婷 贵州省人民医院 中心实验室 Email 摘要 目的 探讨泌尿生殖道支原体感染现状及对抗抗菌药物的敏感性，以期对临床治疗提供依据，以利于针对性治疗与合理用药。方法 应用支原体试剂盒对标本进行培养和药敏试验。 结果 2119例标本中检出311例阳性，总检出率14.7%其中男性检出率11.6%，女性检出率17.8%。解脲脲原体（Uu）、人型支原体（Mh）混合型（Uu+Mh）检出率分别为83.0%、1.3%、15.8%。Uu对抗菌药物敏感率》80%的有强力霉素、美满霉素、交沙霉素、克拉霉素；Mh对强力霉素、美满霉素、交沙霉素100%敏感；Uu+Mh对抗菌药物敏感率80%的有强力霉素、美满霉素、交沙霉素。结论 支原体感染中，以Uu感染为主，女性高于男性，感染可选用克拉霉素、交沙霉素、强力霉素、美满霉素，不宜选用氧氟沙星、左旋氧氟沙星。 关键词 支原体感染 泌尿生殖道 药物敏感性 Ureaplasma urealyticum and Mycoplasma hominis infection detection and clinical significance of treatment The Central Laboratory of Guizhou Peoples Hospital GUI YANG 550002 PU HAI JIN TING TING Abtract:Objective Study on mycoplasma infection status and drug susceptibility, in order to provide basis for clinical treatment, to facilitate targeted treatment and rational use of drug.Methods The mycoplasma cultivation,identification and susceptibility testing were performed by using Mycoplasma reagent kit.Results 2119 specimens were positive in 311 cases, The total positive rate was 14.7%, The prevalence of male 11.6%, female 17.8% detection rate, Ureaplasma urealyticum, Mycoplasma hominis (Uu) (MH), and combination infection of Uu and Mh detection rates were 83%, 1.3%, 15.8%, UU on sensitivity rate of 80% with minocycline, doxycycline, josamycin, clarithromycin, MH, on sensitive rate of 100% with minocycline, doxycycline, josamycin, Combination infection of Uu and Mh on sensitivity rate of 80% with minocycline, doxycycline, josamycin,Conclusion . In Mycoplasma infection , Mainly infected by ureaplasma uxealycicum, females than males, Infection can choose clarithromycin, josamycin, minocycline, doxycycline, For the selection of ofloxacin and levofloxacin. Key words: Mycoplasma infection genitourinary tract?sensitivity test 支原体（mycoplasma）是一种能独立生活的原核细胞微生物，临床以解脲脲原体（ureaplasma uxealycicum，Uu）及人型支原体（mycoplasma hominis，Mh）最常见，易引起泌尿生殖道感染。在女性多引起阴道炎、宫颈炎、子宫内膜炎、卵巢炎、输卵管炎、非淋球菌性尿道炎等疾病，男性可引起非淋球