跨王国化学通信驱动了一种可遗传机制nihms.pdfVIP

HHSPublicAccess

Authormanuscript

ACell.Authormanuscript;availableinPMC2015August28.

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Publishedinfinaleditedformas:

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rCell.2014August28;158(5):1083–1093.doi:10.1016/j.cell.2014.07.025.

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cCross-kingdomchemicalcommunicationdrivesaheritable,

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tmutuallybeneficialprion-basedtransformationsofmetabolism

#1,%#1,2,#34

DanielF.Jarosz,JessicaC.S.Brown,GordonA.Walker,ManoshiS.Datta,W.

51,☩1,2,25

LloydUng,AlexK.Lancaster,AmeliaChang,GregoryA.Newby,DavidA.Weitz,

LindaF.Bisson3,*,andSusanLindquist1,2,6,*

1WhiteheadInstitute,9CambridgeCenter,CambridgeMA,02142

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tMITDepartmentofBiology,77MassachusettsAvenue,Cambridge,MA02139

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UniversityofCalifornia,Davis,DepartmentofViticultureandEnology,77MassachusettsAvenue

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aCambridge,MA02139

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sMITComputationalandSystemsBiologyInitiative,77MassachusettsAvenueCambridge,MA

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02139

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5HarvardUniversityDepartmentofPhysics,4000JonesBridgeRd,ChevyChase,MD20815

6HowardHughesMedicalInstitute,4000JonesBridgeRd,ChevyChase,MD20815

#Theseauthorscontributedequallytothiswork.

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SUMMARY

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hInexperimentalscience,organismsareusuallystudiedinisolation,butinthewildtheycompete

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