Quercetin-d3-hydrate-生命科学试剂-MCE.pdf

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Quercetin-d3hydrate

Cat.No.:HY-18085AS

分⼦式:C₁₅H₉D₃O₈

分⼦量:323.27

作⽤靶点:PI3K;Autophagy;Mitophagy;Apoptosis;ReactiveOxygen

Species

作⽤通路:PI3K/Akt/mTOR;Autophagy;Apoptosis;

Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验DMSO:30mg/mL(92.80mM;Needultrasonicandwarming)

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM3.0934mL15.4669mL30.9339mL

5mM0.6187mL3.0934mL6.1868mL

10mM0.3093mL1.5467mL3.0934mL

BIOLOGICALACTIVITY

⽣物活性Quercetin-d3hydrate是⼀种氘代的Quercetinhydrate(HY-18085A)，是⼀种能刺激重组SIRT1的类黄酮

，同时也是⼀种PI3K抑制剂，其对PI3Kγ、PI3Kδ和PI3Kβ的IC50值分别为2.4μM、3.0μM和5.4μ

M[1]。

IC50Tar