美国肥胖真实世界研究使用6个月患者46.3%.pdfVIP

美国肥胖真实世界研究使用6个月患者46.3%.pdf

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RESEARCHBRIEF1

Real-worldpersistenceandadherenceto

glucagon-likepeptide-1receptoragonists

amongobesecommerciallyinsuredadults

withoutdiabetes

PatrickP.Gleason,PharmD,BCPS;BenjaminY.Urick,PharmD,PhD;LandonZ.Marshall,PharmD,PhD;

NicholasFriedlander,PharmD;YangQiu,MS;R.ScottLeslie,MPH,PhD

PlainlanguagesummaryImplicationsforAuthoraffiliation

managedcarepharmacy

ThisstudyassessedifpeoplewithoutPrimeTherapeutics,LLC,Eagan,MN.

diabetesstayedonglucagon-likepeptide-1DuringthefirstyearofGLP-1therapyfor

(GLP-1)therapyforweightlossandiftheyweightloss,two-thirdsofcommerciallyAUTHORCORRESPONDENCE:

tookitasintended.At1year,among4,066insuredmemberswerenonpersistent,definedPatrickP.Gleason,1.612.777.5190;

people,wefound1in3stayedontheirasamorethan60-daygap,andonly27%pgleason@

GLP-1and27%tooktheirmedicationaswereadherent.GLP-1therapypersistence

intended.WefoundsomeGLP-1productsvariedbetweenproducts.Thesefindingsof

wereassociatedwithmorepeoplestayingpoorpersistenceandadherencewillaidin

ontherapythanothers.ReasonsforlowassessingGLP-1products’cost-effectiveness,

ratesofstayingonGLP-1therapymayunderstandingobesitycaremanagement

includeshortagesaswellassideeffects.programneeds,forecastingfutureGLP-1

useand

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