骨巨并病理性骨折.pptxVIP

骨巨并病理性骨折;Backgroud;对于骨巨伴病理性骨折的外科手术治疗，部分文献认为边缘切除可大大降低局部复发率，从而作为外科首选[1]。且病理性骨折被认为是局部复发的高危因素[2]。因为骨折使得瘤细胞污染周围软组织。 1.Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS. Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Joint Surg Am. 1999;81:811–820. 2. O’Donnell RJ, Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. J Bone Joint Surgam. 1994;76:1827–1833. ;;Advancement;4. Dreinho¨fer KE, Rydholm A, Bauer HC, Kreicbergs A. Giant-cell tumours with fracture at diagnosis. Curettage and acrylic cementing in ten cases. J Bone Joint Surg Br. 1995;77:189–193.;Advancement;6. Balke M, Schremper L, Gebert C, Ahrens H, Streitbuerger A, Koehler G, Hardes J, Gosheger G. Giant cell tumor of bone: treatment and outcome of 214 cases. J Cancer Res Clin Oncol.2008;134:969–978. 7. Errani C, Ruggieri P, Asenzio MA, Toscano A, Colangeli S,Rimondi E, Rossi G, Longhi A, Mercuri M. Giant cell tumor of the extremity: a review of 349 cases from a single institution.Cancer Treat Rev. 2010;36:1–7. 8. Kivioja AH, Blomqvist C, Hietaniemi K, Trovik C, Walloe A, Bauer HC,Jorgensen PH, Bergh P, Folleras G. Cement is recommended in intralesional surgery of giant cell tumors: a Scandinavian Sarcoma Group study of 294 patients followed for a median time of 5 years. Acta Orthop. 2008;79:86–93. 9. Turcotte RE, Wunder JS, Isler MH, Bell RS, Schachar N, Masri BA, Moreau G, Davis AM. Giant cell tumor of long bone: a Canadian Sarcoma Group study. Clin Orthop Relat Res. 2002;397:248–258. 11. Ghert MA, Rizzo M, Harrelson JM, Scully SP. Giant-cell tumor of the appendicular skeleton. Clin Orthop Relat Res. 2002;400:201–210. 12. Prosser GH, Baloch KG, Tillman RM, Carter SR, Grimer RJ.Does curettage without adjuvant therapy provide low recurrence rates in giant-cell tumors of bone? Clin Orthop Relat Res.2005;435:211–218. 13. Szendroi M. Giant-cell tumour of bone. J Bone