液相色谱-串联质谱法检测水产品中磺胺类和喹诺酮类药物残.PDFVIP

26 4 V ol126 N o14 2007 7 FEN X I CESH I XU EBAO ( Journal of Ins trum en tal A naly s s) 508~ 5 10 - 李佐卿, 倪梅林, 俞雪钧, 章再婷, 谢东华, 殷居易, 湛 嘉 ( , 3 150 12) : - (H PLC - M S /M S) , , , - 12 01 05~ 018 mg /L, r = 01 987 5~ 01999 1, 6 1% ~ 104% , ( R SD ) 41 75% ~ 6112% ( n = 5) , 10 ~ 50 Lg / kg : - ; ; ; ; : O 6571 63; R 97812 : A : 1004 - 4957 ( 2007) 04 - 050 8- 03 D eterm nat on o f R es dua l Su lfas and Q u nolones n A quat c Products by HPLC - M S /M S U s ng D euter um R eagen t as Internal Standard L I Zuo-q ng, N IM e- l n, YU X ue-jun, ZHANG Z a-t ng, X IE Dong-hua, Y IN Ju-y , ZHAN J a ( N ngbo A dm n strat on fo r Entry - Ex t Inspect on and Quaran t ne, N ngbo 3 150 12, Ch na) Ab stract: Th s paper descr bes anH PLC - M S /M S m ethod for the determ nat on o f res dua l su lfas and qu no lones n aquat c products. T he ant b o t cs n the sam plesw ere ex tracted w th aceton tr le, and the ex tracts w ere defatted and pur f ed us ng hexane and then concentrated by evaporat on. The res dues w ere d sso lved n the m ob le phase. Su lfas and qu nolones w ere w e ll separated us ng grad ent e lut on. The ant b ot cs w ere detected by H PLC- M S /M S and the deuter um reagent w as u sed as nterna l stand- ard. The l near ty o f standard curves w as m a nta ned n the range of 0105- 018 m g /L, w th the regres- s on coeff c ents r = 01987 5 - 01999 1. The average recover es from labo ratory sp k ng experm ents w ere 61% - 104% , w th relat ve standard dev at ons