b Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice 抗免疫攻击的B细胞在nod小鼠自身免疫性糖尿病进展过程中形成。.pdfVIP
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Article b Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice Graphical Abstract Authors Jinxiu Rui, Songyan Deng, Arnon Arazi, Ana Luisa Perdigoto, Zongzhi Liu, Kevan C. Herold Correspondence kevan.herold@ In Brief Type 1 diabetes (T1D) is due to the immune-mediated destruction of b cells. Rui et al. identify a population of b cells that survives immune attack during T1D progression in non-obese diabetic mice, which may account for the long-term survival of some b cells in patients. Highlights Accession Numbers d Novel b cells with lower granularity develop during GSE94382 progression of T1D in NOD mice d The novel b cells show decreased expression of markers of mature b cells d The novel b cells are protected from immune killing d The novel b cells ar
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