急性中等海拔高原暴露对认知能力影响的研究-内科学（心血管病）专业论文.docx

第三军医大学博士学位论文缩略语表 第三军医大学博士学位论文 缩略语表 英文缩写 英文全称 中文全称 AMS acute mountain sickness 急性高原病 BMI body mass index 体重指数 BP blood pressure 血压 d day 天 DBP diastolic blood pressure 舒张压 h hour 小时 HA lligh altitude 高原 HAH high—altitude headache 高原头痛 HACE high altitude cerebral edema 高原脑水肿 HAH(+) hi曲一altitude headache positive HAIl阳性 HAH(一) high—altitude headache negative HAH阴性 HAPE hi曲altitude pulmonary edema 高原肺水肿 HVR hypoxic ventilatory response 缺氧通气反应 HR heart rate 心率 LLS louise lake score 路易斯湖评分 mln minute 分钟 PoMS profile of mood states 情绪状态评估 SBP systolic blood pressure 收缩压 Sp02 oxygen saturation 氧饱和度 万方数据 第三军医大学博士学位论文Effects 第三军医大学博士学位论文 Effects of Acute Mid··Altitude Exposure on Human Cognitive Ability Abstract Background Human cognitive ability change in response to hypoxia has been the focus of investigation．Hi曲一altitude plateau exposure is accompanied with hypoxia，low pressure， coldness and radiation，which triggers human body protective compensatory reaction through breathing，blood vessels，and metabolic regulation to maintain homeostasis of inner environment．However,human body could not compensate the damage caused by hi曲-altitude exposure or long·time exposure that leads not only to a series of non—specific clinical syndromes such as headache，insomnia，life—threatening high altitude pulmonary edema(HAPE)and high altitude cerebral edema(HACE)，but also the emotional and cognitive neuromotor functional damage．Moreover,hi911-altitude exposure also causes dysfunctional brain metabolism，cerebral vascular regulation and CNS neurons，which flnfiler results in the damage of the white matter microstructural integrity and affects human cognitive ability． Human activities except extreme sports and special tasks in the plateau mostly remain in the mid-altitude area(from 2,43 8 to 4，572 m)，with increasing people traveling，living and working there．During an emergency task such as disaster relief and military activities， high-altitude exposure Can reduce the cognitive capacity of the res